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Figure 1 CoQ provides antioxidant protection to cell membranes and plasma lipoproteins (Lpez-Lluch et al., 2010)

The Insulin-like growth factor 1 receptor (IGF-1R), one of the most intensely investigated kinase targets, is neither mutated in cancers nor did the clinical trials use a molecular-profile based stratification of patients

Chemokines such as CXCL1 and CXCL2 precisely guide neutrophils toward inflammatory sites by binding to the CXCR2 receptor

Furthermore, the expansion of pathobionts like Peptostreptococcus can generate detrimental metabolites (e.g., indole derivatives), which directly upregulate cartilage-degrading MMP-13 (2628)

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